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Previous studies in symptomatic patients and asymptomatic gene-carriers of Huntington's disease (HD) reported a differential deficit in the recognition of facial expressions of disgust. This impairment may point to involvement of the basal ganglia in the recognition of disgust. In this study, we compared the performance of 20 patients with symptoms of HD,(More)
  • A H Lamb
  • 1984
In the developing embryo, 50% or more of the young motoneurons supplying the limb die. Amputation studies suggest that motoneurons depend on acquiring trophic factors from the limb. However, access to the trophic factors is under complex control since all motoneurons, whether destined to live or die, send axons into the limb. Axon invasion is not random but(More)
Chick embryo wing buds were transplanted to the pelvic region in place of, or in addition to, the hindlimb bud prior to innervation. The wrist muscle ulnimetacarpalis dorsalis (umd) was innervated by middle-dorsal or middle-ventral motoneurons in the lumbar lateral motor column (LMC) in a rostrocaudal position which varied with the rostrocaudal position of(More)
The chick wrist muscle ulnimetacarpalis dorsalis (umd) has two heads. Using myosin ATPase and acetylcholinesterase (ACh.E) staining it was shown that one of the heads is composed almost entirely of acid-stable muscle fibres with multiple end plates (slow muscle fibres) and the other of acid-labile fibres with single end plates (fast muscle fibres). The(More)
BACKGROUND We previously developed the Stroke and Aphasia Quality of Life scale (SAQOL-39) and tested it with people with chronic aphasia. A scale allowing comparisons of quality of life between people with versus without aphasia post-stroke would be of value to clinicians. OBJECTIVES To evaluate the psychometrics of the SAQOL-39 in a generic stroke(More)
There is now considerable evidence that phobic responding is associated with a bias towards expecting aversive or traumatic outcomes following encounters with the phobic stimulus (e.g. Behavioural Brain Sci. 18 (1995) 289-325; Phobias: A Handbook of Theory, Research and Treatment. Wiley, Chichester, 1997). In terms of conditioning contingencies, this can be(More)
Sensory neurons were counted in the hind-limb innervating spinal ganglia on both sides of juvenile Xenopus frogs which, as tadpoles, had had one hind limb bud amputated prior to innervation, and a channel made to allow innervation of the remaining limb bud from both sides. The total number of sensory neurons surviving on the two sides approximated the(More)