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Bacterial two-component systems (TCSs) mediate specific responses to distinct conditions and/or stresses. TCS interactions are highly specific between cognate partners to avoid unintended cross-talk. Although cross-talk between a sensor kinase and a noncognate response regulator has been previously demonstrated, the majority of reported interactions have(More)
Uropathogenic Escherichia coli (UPEC), which accounts for 85% of urinary tract infections (UTI), assembles biofilms in diverse environments, including the host. Besides forming biofilms on biotic surfaces and catheters, UPEC has evolved an intracellular pathogenic cascade that culminates in the formation of biofilm-like intracellular bacterial communities(More)
In response to the unique characteristics of Web systems, suitable software engineering approaches need to be utilized to achieve the quality attributes that are specifically required by Web system development. As an important part of this supporting environment, modelling languages for Web systems need to support not only the modelling of both information(More)
OBJECTIVE To perform a systematic review and meta-analysis to study the magnitude of the placebo effect associated with sham surgery procedures. STUDY DESIGN AND SETTING We conducted a systematic search for randomized controlled clinical trials comparing any type of surgery to a corresponding sham placebo group and compared improvements in the sham(More)
BACKGROUND AND AIMS Hyperphosphatemia is an independent predictor for cardiovascular and all-cause mortality in patients undergoing peritoneal dialysis (PD). The study aimed to investigate the effect of dietary intervention on reducing serum phosphate concentration in hyperphosphatemic PD patients. METHODS AND RESULTS In this single-center clinical trial,(More)
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