Alice Cline Parker

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Glial cells play an active role in the central nervous system. We present a CMOS neuromorphic circuit as part of the BioRC Biomimetic Real-time Cortex that emulates a glial microdomain, including several neurons interconnected in a small network. The glial cell, an astrocyte, influences neural behavior to stimulate a neuron to fire. Without glial(More)
CMOS neuromorphic circuits are proposed to emulate the role of astrocytes in phase synchronization of neuronal activity. We emulate, to a first order, the ability of slow inwards currents (SICs) evoked by the astrocyte, acting on extrasynaptic N-methyl-D-aspartate receptors (NMDAR) of adjacent neurons, as a mechanism for phase synchronization. We do an(More)
Neuromorphic circuits are designed and simulated to emulate the role of astrocytes in phase synchronization of neuronal activity. We emulate, to a first order, the ability of slow inward currents (SICs) evoked by the astrocyte, acting on extrasynaptic N-methyl-D-aspartate receptors (NMDAR) of adjacent neurons, as a mechanism for phase synchronization. We(More)
Connectivity in the human retina is complex. Over one hundred million photoreceptors transduce light into electrical signals. These electrical signals are sent to the ganglion cells through amacrine and bipolar cells. Lateral connections involving horizontal and amacrine cells span throughout the outer plexiform layer and inner plexiform layer respectively.(More)
Astrocytes, a type of glial cell, have been shown to actively modulate neural activity in the central nervous system. One way in which astrocytes can be stimulated is through receptors of retrograde messengers that are located on the astrocyte processes. Retrograde messengers are released by a neuron's postsynaptic dendrite in response to neural activity,(More)
A CMOS neuromorphic circuit is proposed with two main features. First, we emulate the uptake of neurotransmitters by astrocytes, a type of glial cell, that plays an active role in the coordination of information between neurons. Second, we propose a synapse inactivation mechanism, which prevents the saturation of postsynaptic neurons in the absence of an(More)
Though much is known about how binocular neurons in the primary visual cortex respond to stereo imagery, there has yet to be a consensus on how these responses are actually used to compute stereo disparity, the difference in the position of an object between the right image and left image in a stereo pair. We describe a new theory for neural stereo(More)
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