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FMR1 premutation carriers are common in the general population (1/130-260 females and 1/250-810 males) and can be affected by fragile X-associated tremor ataxia syndrome, fragile X-associated primary ovarian insufficiency, anxiety, depression, hypertension, sleep apnea, fibromyalgia, and hypothyroidism. Here we report the results of a pilot study to assess(More)
OBJECTIVE To determine the characteristics, causes and outcome of severe hyponatraemia (< 125 mmol/l) in hospitalized patients, and to identify mortality predictors. DESIGN Prospective case controlled study of sequentially presenting patients with a serum sodium (Na) < 125 mmol/l. PATIENTS AND METHODS One hundred and four hyponatraemic and 104 randomly(More)
The incidence and characteristics of HIV-associated lymphoma among a cohort of patients infected predominantly through intravenous drug use are reported. Fifty-one definite cases were identified, occurring in a total cohort of approximately 1,340 individuals. The rate at which lymphoma occurred as the AIDS-defining illness did not differ significantly from(More)
e15678 Purpose: To evaluate the prevalence of depression, sleep related disturbances and anxiety and their effect on quality of life in patients with recently diagnosed adenocarcinoma of the pancreas who present to a multidisciplinary pancreatic cancer clinic. METHODS Cross-sectional and longitudinal psychosocial distress was assessed utilizing Personal(More)
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