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NK cells are enriched in the liver, constituting around a third of intrahepatic lymphocytes. We have previously demonstrated that they upregulate the death ligand TRAIL in patients with chronic hepatitis B virus infection (CHB), allowing them to kill hepatocytes bearing TRAIL receptors. In this study we investigated whether, in addition to their pathogenic(More)
UNLABELLED Emerging therapies for chronic hepatitis C viral (HCV) infection involve inhibition of viral enzymes with drug combinations. Natural, or treatment-induced, enzyme polymorphisms reduce efficacy. We developed a phenotyping assay to aid drug selection based on viral transfer from monocytes to hepatocytes. We studied HCV in monocytes from infected(More)
In vitro toxicological influence of culture filtrates of Fusarium oxysporum f. sp. lycopersici (Sacc.) Snyder & Hans was investigated on seed germination, seedling growth and physiology of tomato (Lycopersicum esculentum Mill.) under chromium(VI) stress. Original culture filtrates of the fungus and three concentrations of Cr(VI) viz. 50, 75 and 100 mg L1(More)
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