Ali-Reza Sharif-Afshar

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Transforming growth factor–B (TGF-B) isoforms are growth factors that function physiologically to regulate development, cellular proliferation, and immune responses. The role of TGF-B signaling in mammary tumorigenesis is complex, as TGF-B has been reported to function as both a tumor suppressor and tumor promoter. To elucidate the role of TGF-B signaling(More)
PURPOSE To improve spatial resolution and image quality of diffusion-weighted (DW) MRI in detecting low-risk prostate cancer (lrPC) in patients undergoing active surveillance protocol (AS-PC), we propose the application of a diffusion-prepared balanced steady-state free precession (bSSFP) technique capable of multishot acquisition. METHODS(More)
OBJECTIVES High-resolution prostate imaging may allow for detection of subtle changes in tumor size, decrease the reliance on biopsies, and help define tumor boundaries during ablation. This pilot clinical trial evaluates a novel high-resolution prostate MRI for detection of small, biopsy-proven prostate tumors. METHODS Our team developed a software that(More)
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