Learn More
The present study was undertaken to determine the therapeutic effect of the culture filtrate of Cryptococcus neoformans var. gattii (CneF) in experimental immune complex glomerulonephritis. Bovine serum albumin (BSA) nephritis was induced in rats by a subcutaneous immunization and daily intravenous administration of BSA. CneF solution at three different(More)
Despite the successful outcome of anti-D prophylaxis program, alloimmunization still occurs. The aim of this study was to examine the specificity and isotype of anti-Rh antibodies in plasma samples of Rh negative alloimmunized individuals and to study the same parameters in lymphoblastoid cell lines (LCLs) generated from the same donors. Specificity of(More)
We examined the efficacy of the culture filtrate of Cryptococcus neoformans var. gattii (CneF) as a novel anti-inflammatory compound in experimental septic arthritis. Haematogenously infectious arthritis was induced in rats by a single intravenous injection of 109 CFU Staphylococcus aureus producing toxic shock syndrome toxin-1. CneF solution at two(More)
Model Transformation is considered an important enabling factor for Model Driven Development. Transformations can be applied not only for the generation of new models from existing ones, but also for the consistent co-evolution of software artifacts that pertain to various phases of software lifecycle such as requirement models, design documents and source(More)
The potential therapeutic effect of low-viscosity sodium alginate (LVA) was studied in a rat model of acute colitis induced by intracolonic administration of acetic acid. This experimental model produced a significant ulcerative colitis. Induction of colitis also significantly enhanced the serum and colonic mucosal cytokine (IL-6 and TNF-alpha) and(More)
UNLABELLED The therapeutic efficacy of novel designed nonsteroidal anti-inflammatory drug, M2000 (beta- D- mannuronic acid) on experimental immune complex glomerulonephritis was evaluated. Bovine serum albumin (BSA) nephritis was induced in rats by a subcutaneous immunization and daily intravenous administration of BSA. M2000 solution (30 mg/kg) was(More)
UNLABELLED The present research introduces the method of Production of M2000 (β-d-mannuronic acid) and its therapeutic effect on experimental model of nephritis. M2000 was produced using enzymatic and chemical procedure on prepared alginate from Pseudomonas fluorescens. The experimental glomerulonephritis was induced in rats by a subcutaneous immunization(More)
The component-based nature of large industrial software systems that consist of a number of diverse collaborating applications, pose significant challenges with respect to system maintenance, monitoring, auditing, and diagnosing. In this context, a monitoring and diagnostic system interprets log data to recognize patterns of significant events that conform(More)
Most modern model driven software development environments rely heavily on model transformations for generating various software design artifacts and eventually even source code. However, during development, maintenance and evolution activities, these software artifacts are subject to updates and refactoring operations. In such model driven development(More)