Ali R Zand

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Butyric acid and trichostatin A (TSA) are anti-cancer compounds that cause the upregulation of genes involved in differentiation and cell cycle regulation by inhibiting histone deacetylase (HDAC) activity. In this study we have synthesized and evaluated compounds that combine the bioavailability of short-chain fatty acids, like butyric acid, with the(More)
The problem of primary and secondary spread of sessile droplets into a porous substrate was formulated and solved numerically. A continuum approach for liquid- and gas-phases was utilized. The governing equations were discretized by finite difference method and solutions for both phases are obtained by marching in time using the fourth-order Runge-Kutta(More)
The surfaces of high-density or ultra-high-molecular-weight polyethylenes were hydroxylated using a two-step process. The wetting and wear properties of the untreated (virgin) and surface hydroxylated polyethylenes were compared. The introduction of hydroxyl groups provided an increase in surface hydrophilicity resulting in reduced wear. Hydrophilicity was(More)
A Computational model to solve the coupled transport equations with chemical reaction and phase change for a liquid droplet between two approaching porous or non-porous surfaces, is developed. The model is general therefore it can be applied to toxic chemicals (contact hazard), drug delivery through porous organs and membranes, combustion processes within(More)
The infiltration of a sessile droplet into a homogeneous porous medium for a constant droplet base radius case is solved numerically, where the porous medium is represented as a capillary network consisting of pores and throats. For a homogeneous medium, the network is built of the spherical pores of constant radius, and the cylindrical throats of constant(More)
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