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This paper is a compendium of exact and asymptotic formulas and tables for calculating the sample size in a clinical trial for a matched-pair design involving a dichotomous outcome. Formulas for calculating power given the sample size are also given.
This paper is a compendium of exact and asymptotic formulae and tables for estimating the sample size in a clinical trial with two treatment groups and a dichotomous outcome. The paper provides separate formulae for equal and unequal treatment group sizes, formulae for the calculation of power given the sample size, and complete references for all formulae… (More)
Fisher's exact test and Pearson's chi-square with continuity correction are frequently employed in the analysis of epidemiological data involving a 2 x 2 contingency table. This paper reviews the concepts and controversies underlying these procedures and discusses their appropriateness and adequacies in analyzing such data. Other related procedures such as… (More)
Some methods of constructing confidence intervals for the probability of success in a hypergeometric distribution are described and illustrated with examples. To assist the readers in implementing the procedures, pertinent information on special tables and computer programs is provided that can be readily employed with little or no additional computation.
Sulfate-reducing bacteria have been implicated in inflammatory bowel diseases and ulcerative colitis in humans and there is an interest in inhibiting the growth of these sulfide-producing bacteria. This research explores the use of several chelators of bismuth to determine the most effective chelator to inhibit the growth of sulfate-reducing bacteria. For… (More)
(2014) A comparative study of Takaful and conventional insurance:empirical evidence from the Malaysian market. Users may access full items free of charge; copies of full text items generally can be reproduced, displayed or performed and given to third parties in any format or medium for personal research or study, educational or not-for-profit purposes… (More)