Learn More
BACKGROUND Hemoglobinopathy and thalassemia are prevalent genetic disorders throughout the world. Beta thalassemia is one of these disorders with high prevalence in Iran, especially in Khuzestan province. In this study, the rate of different mutations in β-globin gene for prenatal diagnosis in fetal samples was evaluated. MATERIALS AND METHODS In this(More)
Context Inherited hemoglobin diseases are the most common single-gene disorders. Induction of fetal hemoglobin in beta hemoglobin disorders compensate for abnormal chain and ameliorate the clinical complications. Sodium butyrate is used conventionally for fetal hemoglobin induction; it can be replaced by safer therapeutic tools like microRNAs, small(More)
LETTER TO EDITOR Mesenchymal stem cells (MSCs) are pluripotent stem cells with high capacity of self-renewal and expansion, with differentiation potential to various cells including osteoblasts, 1 The approach of reconstructive medicine and tissue engineering demands designing biocompatible scaffolds, clinical use of which has the lowest level of side(More)
LETTER TO ETITOR G6PD (Glucose-6-Phosphate Dehydrogenase) enzyme deficiency is the most common inherited enzyme deficiency so far reported. 1 This enzyme deficiency affects 400 million people worldwide. 2 Most cases of the disease are from tropical regions of Africa, the Middle East, tropical and subtropical regions of Asia and the Mediterranean margin,(More)
  • 1