Alfredo Cano

  • Citations Per Year
Learn More
INTRODUCTION Nucleoside reverse transcriptase inhibitor (NRTI) is associated with endothelial dysfunction and proinflammatory effects. Maraviroc (MVC) is an antagonist of CCR5 receptor. CCR5 is the receptor of RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted), a mediator of chronic inflammation and endothelial function. Our aim was to(More)
INTRODUCTION Inversion of the CD4:CD8 ratio (<1) has been identified as a hallmark of immunosenescence and an independent predictor of mortality in the general population. We aimed to assess the association between the CD4:CD8 ratio and intima-media thickness (IMT) progression in treated HIV-infected patients as a marker of early atherosclerosis. (More)
Inversion of the CD4/CD8 ratio (<1) has been identified as a surrogate marker of immunosenescence and an independent predictor of AIDS events in HIV-infected patients and mortality in the general population. We aimed to assess the association between the CD4/CD8 ratio and carotid intima-media thickness (cIMT) progression in treated HIV-infected patients as(More)
BACKGROUND AND OBJECTIVE To study the association between hypertriglyceridemic waist phenotype and the presence of subclinical atherosclerosis in human immunodeficiency virus (HIV) infected patients. PATIENTS AND METHODS Cross sectional study. Hypertriglyceridemic waist phenotype was considered if the waist was ≥90cm and triglycerides ≥2.0mmol/l(More)
Region transformation methods have been used by many authors to integrate singular multivariate integrands, the most notable being the Duffy transformation that maps squares onto triangles and cubes onto pyramids. In this paper, a new method that generalizes and improves the existing ones is provided. We show that behind these variable transformation(More)
This paper presents a sustainability assessment model based on requirement trees, value analysis, the Analytic Hierarchy Process, and the Monte Carlo simulation technique. It embraces the approach for assessing sustainability taken by the Spanish Structural Concrete Code. Nevertheless, the deterministic model of the Spanish Code can cause significant(More)
Dear Editor: Patients with HIV infection have an increased mortality, largely attributable to cardiovascular disease (CVD). In addition to traditional and not traditional cardiovascular risk factors, HIV infection and antiretroviral therapy (ART) have also been implicated in the premature development of atherosclerosis and coronary heart disease. There is(More)
  • Alfredo Cano, Garcinuño Villamuriel De Cerrato, +60 authors Garcinuño
The aim of this study was to describe the time patterns of wheezing in both asthmatic and non‐ asthmatic children during the first thirty‐six months, and to determine whether there are asthma‐ related breakpoints in the incidence of wheezing. Data from a historical cohort of children followed from birth to six years (SLAM cohort) were used. Wheezing(More)