Alfredo Buzzi

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A randomized, double-blind, placebo-controlled trial was performed to evaluate the efficacy and safety of thymosin alpha 1 (alpha 1) in treating chronic hepatitis C. Nineteen Italian patients with chronic active hepatitis C, proven by biopsy were randomly assigned to receive a six month course of thymosin alpha 1 (900 micrograms/m2 of body surface area(More)
HIV-induced cytokine dysregulation, including overproduction of the antiproliferative and cytolytic IFN alpha cytokine, represents a major component of the immune disorders characterizing AIDS. To block the overproduction of IFN alpha we designed an AIDS vaccine combination which included both an anti-HIV and/or an anti-IFN alpha immunization. The safety(More)
One ovarian mucinous cystic tumor that contained a mural solid nodule of anaplastic carcinoma is described in a 35-year-old woman. The epithelial elements consisted of invasive well differentiated mucinous carcinoma. The anaplastic nodule showed some similarities with the cells described in sarcoma and sarcoma-like mural nodules. In favor of a diagnosis of(More)
BACKGROUND Several studies have shown that Helicobacter pylori infection is associated with enhanced gastric epithelial-cell proliferation, which is thought to be involved in its apparent carcinogenicity. This hyperproliferation is believed to be related to the inflammatory effects of the bacterium. The role of Helicobacter pylori in gastric epithelial(More)
We report one example of mature cystic teratoma of the ovary containing prostatic tissue, in a 73 year-old female. The tumor is typical and it is composed of well-differentiated derivatives of the three germ layers. Prostatic tissue was an incidental finding in teratoma. This tissue contained ducts and acini in a simple branching pattern similar to that(More)
Activation of the arachidonic acid metabolism seems to be one of the post-receptor mechanisms by which interferon-alpha induces antiviral protein synthesis. In this study, we evaluated the changes on serum 2'5'-oligoadenylate synthetase levels induced by acute administration of interferon-alpha, indomethacin and interferon-alpha plus indomethacin in 21(More)