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A number of methods have been described for the estimation of peptic activity, many of which are accurate and convenient for comparative experiments but none of which give results which are accurately reproducible with different preparations of the protein used. This variation is due to the difficulty involved in obtaining reproducible protein preparations(More)
The viscosity of a protein solution is increased by the denaturation of the protein. This is true both when there is the formation of protein aggregates which occlude water and when there is no aggregation. Under certain conditions, as a result of the aggregation following denaturation, a solution containing only one per cent of protein may be converted(More)
Lampbrush chromosomes have been observed in the growing odcytes of animals ranging from mollusks to mammals. They are present throughout the diplotene of the first meiotic division. These elongate, paired structures bear many thousands of loops projecting laterally from the main chromosomal axis, and they are characteristically accompanied in the nuclear(More)
(Interview Transcription) I am Bruce McEwen, professor and head of the Laboratory of Neuroendocrinology at the Rockefeller University here in Manhattan. Question: What are the most important recent findings from neuroscience and epigenetic research with regard to the epidemic levels of child maltreatment and violence against children, especially also with(More)
The denaturation of hemoglobin by salicylate in neutral solution is completely reversible. There is a mobile equilibrium between native and denatured hemoglobin in neutral salicylate solution. The higher the salicylate concentration the greater is the percentage denaturation. When there is a mobile equilibrium between the native and denatured forms of a(More)
  • Tm Bonner, J Huang, Marushige K Tuan, D Y H, Dept Biol, Johns Hopkins +5 others
  • 2004
This paper is a comprehensive review of chroma-tin biology and chemistry as seen in 1968, or eight years after the beginning of this science. Chroma-tin consists of DNA complexed with proteins known as histones. It is shown that histones are comprised of five species which are very much the same in all eukaryotic creatures and conserved in amino acid(More)