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Stereoscopic neuroanatomy lectures using a three-dimensional virtual reality environment.
INTRODUCTION Three-dimensional (3D) computer graphics are increasingly used to supplement the teaching of anatomy. While most systems consist of a program which produces 3D renderings on aExpand
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High-dose tamoxifen treatment increases the incidence of multifocal tumor recurrences in glioblastoma patients.
BACKGROUND Multifocal tumor recurrences in glioblastoma patients are described in 4% - 14% of cases. Two recent studies, treating newly diagnosed glioblastoma patients with continuous high-doseExpand
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Video-Assisted Navigation for Adjustment of Image-Guidance Accuracy to Slight Brain Shift
BACKGROUND: Information supplied by an image-guidance system can be superimposed on the operating microscope oculars or on a screen, generating augmented reality. Recently, the outline of a patient'sExpand
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Navigation and robot-aided surgery in the spine: historical review and state of the art
Spinal anatomy is complex and in close vicinity of vulnerable anatomical structures, such as nerve roots, spinal cord, and blood vessels, requiring high precision in surgical procedures, while theExpand
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Adjuvant temozolomide-based chemoradiotherapy versus radiotherapy alone in patients with WHO III astrocytoma
BackgroundIt is currently unclear whether adjuvant therapy for WHO grade III anaplastic astrocytomas (AA) should be carried out as combined chemoradiotherapy with temozolomide (TMZ)—analogous to theExpand
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RESULTS OF THE INTERNATIONAL INTERLABORATORY COMPARISON OF MGMT PROMOTER METHYLATION ANALYSIS INVOLVING TWENTY-THREE ACADEMIC CENTERS IN GERMANY, AUSTRIA AND THE NETHERLANDS
BACKGROUND: Molecular testing for MGMT promoter methylation has become of clinical importance in the diagnostic assessment of malignant gliomas since test results may guide therapeutic decisionExpand
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RNA-sequencing and bioinformatic analysis to pre-assess sensitivity to targeted therapeutics in recurrent glioblastoma.
e13533Background: This study developed molecular guided tools for individualized selection of chemotherapeutics for recurrent glioblastoma (rGB). A consortium involving clinical neurooncologists, m...
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Perspectives and Challenges in Molecular-Based Diagnostics and Personalized Treatment for Recurrent High-Grade Gliomas
Glioblastoma is the most common and most malignant type of intrinsic brain tumor in adults. The standard of care for glioblastoma consists of surgical debulking followed by combinedExpand
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Comparison of Custom Cranial Implant Source Data: Manual, Mirrored and CAD generated skull surfaces
tl;dr
We compare the accuracy of skull defect contours generated by CT volume mirroring and CAD. Expand
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Three-dimensional Cross-Platform Planning for Complex Spinal Procedures: A New Method Adaptive to Different Navigation Systems
tl;dr
We developed a method based on the DICOM standard which transfers complex 3-dimensional trajectories and objects from external planning software to any navigation system for planning and intraoperative guidance of complex spinal procedures. Expand
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