Alexsandro R. Meireles

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We investigated the efficacy of danazol treatment in eight patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). Treatment with danazol yielded clinical improvement of urinary control and gait disturbances in 7 out of the 8 patients. The improvement was noted within 15 days of danazol administration. Analysis of factors of(More)
The p-centre phenomenon is revisited here under a dynamical paradigm. It is our contention that p-centres can be seen as the projection onto the time axis of an underlying phrase stress oscillator inferred during the realisation of the task of producing (and perceiving) a sequence of syllables in time with a metronome. In this kind of inference, vowel(More)
This acoustic study investigates speech rhythmic restructurings due to speech rate increase in Brazilian Portuguese. Rhythmic restructuring is considered here as the reorganization of stress groups due to speech rate increase. The Dynamical Speech Rhythm model was used as a theoretical background for the acoustic analyses. Main results have shown that(More)
Recent studies of tropical spastic paraparesis have confirmed the existence of human T-cell leukemia virus type-1 (HTLV-I) in several tropical areas of the world. In order to determine the role of HTLV-I as an etiologic agent of myelopathies in Salvador, we conducted a clinical and serological study in 43 patients with non-traumatic and non-tumoral(More)
This paper discusses new inventive methodologies for the classification of speech rhythms. Moreover, it sheds new light in the search for isochrony in speech by showing that fast rates exacerbates the timing characteristics of rhythms, i.e., syllable-and/or stress-timing properties are more easily perceived at these rates. This finding is supported by an(More)
This paper analyzes the speech rhythm of three Brazilian Portuguese dialects under the light of a coupled oscillator approach to rhythm typology. The data showed a scale from a less stress-timed to a more stressed-timed dialect as follows: Minas Gerais state (coupling strength = 1.83, speech rate = 6.3) > São Paulo state (1.66, 6.6) > Bahia state (1.26,(More)
The coordination of velum and lingual gestures for Brazilian Portuguese nasal vowels in CV syllables is studied with real-time magnetic resonance imaging (rt-MRI). Four syllable structures were compared: stop-oral vowel, stop-nasal vowel, nasal-oral vowel, nasal-nasal vowel. Results show near-synchrony timing (in-phase) for the consonant onset and nasal(More)