Alexis Lamiable

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We present an algorithm for automatically predicting the topological family of any RNA three-way junction, given only the information from the secondary structure: the sequence and the Watson-Crick pairings. The parameters of the algorithm have been determined on a data set of 33 three-way junctions whose 3D conformation is known. We applied the algorithm(More)
Structure determination of linear peptides of 5-50 amino acids in aqueous solution and interacting with proteins is a key aspect in structural biology. PEP-FOLD3 is a novel computational framework, that allows both (i) de novo free or biased prediction for linear peptides between 5 and 50 amino acids, and (ii) the generation of native-like conformations of(More)
We present a new approach for the prediction of the coarse-grain 3D structure of RNA molecules. We model a molecule as being made of helices and junctions. Those junctions are classified into topological families that determine their preferred 3D shapes. All the parts of the molecule are then allowed to establish long-distance contacts that induce a 3D(More)
Private Mobile Radio (PMR) networks are cellular infrastructures dedicated to be used by professionals, such as public safety, military, industry and transportation organizations. In those networks, resources are scarce, and there are strong Quality of Service (QoS) requirements. The emergence of new services which need more bandwidth has made the world PMR(More)
The blind identification of candidate patches of interaction on the protein surface is a difficult task that can hardly be accomplished without a heuristic or the use of simplified representations to speed up the search. The PEP-SiteFinder protocol performs a systematic blind search on the protein surface using a rigid docking procedure applied to a limited(More)
Hidden Markov Model derived structural alphabets are a probabilistic framework in which the complete conformational space of a peptidic chain is described in terms of probability distributions that can be sampled to identify conformations of largest probabilities. Here, we assess how three strategies to sample sub-optimal conformations-Viterbi k-best,(More)
Private Mobile Radio (PMR) networks are cellular infrastructures dedicated to be used by professionals, such as public safety, military, industry and transportation organizations. The world PMR leader, Airbus Defence and Space (former Cassidian), intends to base the next generation of its products upon LTE-Advanced, enriched with a new sensing method which(More)
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