Alexey Verkhovsky

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A method is presented that reliably detects spherical viruses from a wide variety of noisy low-contrast electron micrographs. Such detection is one of the first image analysis steps in the computer-aided reconstruction of three-dimensional density distribution models of viruses. Particle detection is based on the comparison of intensity in a circular area(More)
Crawling of animal cells over surfaces is based on three coupled mechanisms: protrusion of the leading edge, graded adhesion to the substratum and forward translocation of the cell body. The most important of these, the forward translocation, or traction, is powered by myosin in many cases. We discuss existing experimental results and theories of traction(More)
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