• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage your publications. Semantic Scholar automatically creates author pages based on data aggregated from public sources and our publisher partners.
  • J J Shatzel, Sven R Olson, Derrick L Tao, Owen J T McCarty, Alexey V. Danilov, Thomas G DeLoughery
  • Medicine
  • Journal of thrombosis and haemostasis : JTH
  • 2017 (First Publication: 1 May 2017)
  • Ibrutinib is an irreversible inhibitor of Bruton's tyrosine kinase (Btk) that has proven to be an effective therapeutic agent for multiple B-cell-mediated lymphoproliferative disorders. Ibrutinib,Continue Reading
  • J Claire Godbersen, Leigh Humphries, +4 authors Alexey V. Danilov
  • Biology, Medicine
  • Clinical Cancer Research
  • 2014 (First Publication: 14 March 2014)
  • Background: Stromal-mediated signaling enhances NF-κB pathway activity in chronic lymphocytic leukemia (CLL) B cells, leading to cell survival and chemoresistance. Ubiquitination of IκBα mayContinue Reading
  • Suresh Kumar Agarwal, Ahmed Hamed Salem, +6 authors Shekman L. Wong
  • Medicine
  • British journal of clinical pharmacology
  • 2017 (First Publication: 1 April 2017)
  • AIMS To examine the effect of a strong cytochrome P450 (CYP) 3A inhibitor, ketoconazole, on the pharmacokinetics, safety and tolerability of venetoclax. METHODS Twelve patients with non‐HodgkinContinue Reading
  • Cláudia Paiva, J Claire Godbersen, Alice H. Berger, Jennifer R Brown, Alexey V. Danilov
  • Biology, Medicine
  • Cell Death and Disease
  • 2015 (First Publication: 1 July 2015)
  • Microenvironment-mediated upregulation of the B-cell receptor (BCR) and nuclear factor-κB (NF-κB) signaling in CLL cells resident in the lymph node and bone marrow promotes apoptosis evasion andContinue Reading
  • Ryan S. Soderquist, Alexey V. Danilov, Alan Eastman
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2014 (First Publication: 28 April 2014)
  • Background: The mechanism through which gossypol mediates anti-cancer activity is poorly understood. Results: Gossypol rapidly activates phospholipase A2, increases cytoplasmic calcium, endoplasmicContinue Reading