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  • Renata Basto, Joyce Lau, +4 authors Jordan W. Raff
  • Biology, Medicine
  • Cell
  • 2006 (First Publication: 1 June 2006)
  • Centrioles and centrosomes have an important role in animal cell organization, but it is uncertain to what extent they are essential for animal development. The Drosophila protein DSas-4 is relatedContinue Reading
  • Matthieu Piel, Pablo Meyer, Alexey Khodjakov, Conly L. Rieder, Michel Bornens
  • Medicine, Biology
  • The Journal of cell biology
  • 2000 (First Publication: 17 April 2000)
  • We have generated several stable cell lines expressing GFP-labeled centrin. This fusion protein becomes concentrated in the lumen of both centrioles, making them clearly visible in the living cell.Continue Reading
  • Petr Strnad, Sebastian Leidel, Tatiana Vinogradova, Ursula Euteneuer, Alexey Khodjakov, Pierre Gönczy
  • Medicine, Biology
  • Developmental cell
  • 2007 (First Publication: 1 August 2007)
  • Centrosome duplication involves the formation of a single procentriole next to each centriole, once per cell cycle. The mechanisms governing procentriole formation and those restricting itsContinue Reading
  • Daniela Cimini, Bonnie Lee Howell, Paul S Maddox, Alexey Khodjakov, Francesca Degrassi, E. D. Salmon
  • Medicine, Biology
  • The Journal of cell biology
  • 2001 (First Publication: 30 April 2001)
  • In mitotic cells, an error in chromosome segregation occurs when a chromosome is left near the spindle equator after anaphase onset (lagging chromosome). In PtK1 cells, we found 1.16% of untreatedContinue Reading
  • Susan L. Kline-Smith, Alexey Khodjakov, Polla J. Hergert, Claire E. Walczak
  • Biology, Medicine
  • Molecular biology of the cell
  • 2004 (First Publication: 29 December 2003)
  • The complex behavior of chromosomes during mitosis is accomplished by precise binding and highly regulated polymerization dynamics of kinetochore microtubules. Previous studies have implicated KinContinue Reading
  • Alexey Khodjakov, Conly L. Rieder
  • Medicine, Biology
  • The Journal of cell biology
  • 1999 (First Publication: 9 August 1999)
  • γ-Tubulin is a centrosomal component involved in microtubule nucleation. To determine how this molecule behaves during the cell cycle, we have established several vertebrate somatic cell lines thatContinue Reading