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Vessel segmentation in photographies of the retina is needed in a set of computer-supported medical applications related to diagnosis and surgery planning. Considering each pixel in an image as a point in a feature space, segmentation is a binary classification problem where pixels need to be assigned to one of two classes: object and background. We(More)
The detection of changes in image sequences often is the first essential step to video analysis, e.g. for the detection, classification and tracking of moving objects. As a binary classification problem, change detection is afflicted by the trade-off between two class error probabilities, viz. the rates of false positives and false negatives. In this(More)
PURPOSE A microangiographic technique is described, which allows visualization of small blood vessels with a diameter of approximately 20 microm and quantification of fasciocutaneous blood vessels by means of digital computer analysis in very small laboratory animals. METHOD The left carotid artery of 45 nu/nu mice was cannulated (26 gauge) and a mixture(More)
We address the problem of person authentication, including verification and identification, using the vascular network of the retina. We propose a novel feature extraction process that includes the segmentation of feature points related to anatomical characteristics of the retinal vessel-network, the description of these points with the help of the(More)
A number of image analysis tasks of the heart region have to cope with both the problem of respiration and heart contraction. While the heart contraction status can be estimated based on the ECG, respiration status estimation must be based on the images themselves, unless additional devices for respiration measurements are used. Since diaphragm motion is(More)
BACKGROUND Angiogenesis can be enhanced by several growth factors, like vascular endothelial growth factor-165 (VEGF(165)) and basic fibroblast growth factor (bFGF). Delayed release of such growth factors could be provided by incorporation of growth factors in fibrin matrices. In this study, we present a slow release system for VEGF(165) and bFGF in fibrin(More)
BACKGROUND AND AIMS Adjuvant therapies may improve the outcome after nerve reconstruction. We analyzed the influence of recombinant human Erythropoietin (rHuEpo), which has proven angiogenic and neuroprotective effects, on the quality of peripheral nerve regeneration. METHODS Thirty two female Lewis rats underwent nerve reconstruction by means of(More)
Percutaneous transluminal coronary angioplasty (PTCA) requires both pre-interventional cine-angiograms showing the contrasted vessel tree over several heart cycles, and live X-ray monitoring (flu-oroscopy) during the catheterization. Navigation during the intervention can be facilitated by fusing the automatically synchronized cine-angiogram with the(More)