Alexandru Calistru

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In vivo repopulation of decellularized allografts with recipient cells leads to a positive remodeling of the graft matrix in juvenile sheep. In light of the increasing number of heart valve replacements among older patients (>65 years), this study focused on the potential for matrix-guided tissue regeneration in elderly sheep. Pulmonary valve replacement(More)
Galway, Ireland CCN1 Coating Allows Successful Re-Endothelialization of Ovine Decellularized Heart Valves with Endothelial Cells Differentiated from Circulating EPC in vitro Andres Hilfiker, Alexandru Calistru, Tanja Meyer, Axel Haverich Hilfiker.Andres@mh-hannover.de Leibniz Research Laboratories for Biotechnology and Artificial Organs, Hannover, Germany,(More)
Tissue-engineered (TE) grafts based on decellularized grafts have shown very promising results in preclinical and clinical studies. However, in animal models valves have either been tested in juvenile models or in the clinically less relevant pulmonary valve position. In this study, we tested the grafts in the aortic valve (AV) position of 6-year old sheep,(More)
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