Alexandros Skamnelos

  • Citations Per Year
Learn More
BACKGROUND Patients with inflammatory bowel disease (IBD) and human immunodeficiency virus (HIV) infection have shown controversial data concerning the remission hypothesis of IBD due to CD4 count depletion caused by HIV. The aim of our systematic review was to investigate the hypothesis whether low CD4 count due to HIV is related to IBD remission. (More)
BACKGROUND Disease extent in ulcerative colitis is one of the major factors determining prognosis over the long-term. Disease extent is dynamic and a proportion of patients presenting with limited disease progress to more extensive forms of disease over time. AIM To perform a systematic review and meta-analysis of epidemiological studies reporting on(More)
Fast-track drug designation of safe regimens represents an emerging method of development and approval of new medications targeting debilitating diseases including inflammatory bowel diseases (IBD). The goal of accelerated drug approval pathways is to shorten the time between application and approval of therapies that treat diseases with significant(More)
Inflammatory bowel disease (IBD) is a chronic systemic disorder, which mainly affects the bowel. However, both ulcerative colitis (UC) and Crohn’s disease (CD) are often associated with extra intestinal manifestations, complications, and other autoimmune disorders. These manifestations can involve almost any organ system, including the musculoskeletal,(More)
  • 1