Alexandre Sobolevski

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The capability of accurately applying millinewton-level touch stimuli to Drosophila larvae and simultaneously observing their resultant fluorescence responses in mechanosensitive neuron transmission will enable novel studies of mechanotransduction neural circuitry. This paper presents an automated robotic micromanipulation system capable of force-controlled(More)
The nematode worm Caenorhabditis elegans has been employed as a popular model organism in many fields of biological research. In this paper, we present a microfluidic device for facilitating chemical testing using C. elegans. For testing chemicals on chip, the device houses single nematodes in microfluidic chambers and precisely adjusts the chamber's(More)
This paper presents an automated robotic micromanipulation system capable of force-controlled mechanical stimulation and fluorescence imaging of Drosophila larvae, for mechanotransduction studies of Drosophila neural circuitry. An elastomeric microdevice is developed for efficient immobilization of an array of larvae for subsequent force-controlled(More)
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