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The following questions are often encountered in system and control theory. Given an algebraic model of a physical process, which variables can be, in theory, deduced from the input-output behavior of an experiment? How many of the remaining variables should we assume to be known in order to determine all the others? These questions are parts of the… (More)

We exhibit probabilistic algorithms which compute the differentiation index, the differential Hilbert function and an algebraic parametric set associated to a differential rational mapping. These algorithms are based on a process of linearization and specialization in a generic solution, and have polynomial time complexity.

We propose algorithms for the computation of the first <i>N</i> terms of a vector (or a full basis) of power series solutions of a linear system of differential equations at an ordinary point, using a number of arithmetic operations that is quasi-linear with respect to <i>N</i>. Similar results are also given in the non-linear case. This extends previous… (More)

We present a probabilistic seminumerical algorithm that computes the differential Hilbert function associated to a differential rational mapping. This algorithm explicitly determines the set of variables and derivatives which can be arbitrarily fixed in order to locally invert the differential mapping under consideration. The arithmetic complexity of this… (More)

Lie group theory states that knowledge of a m-parameters solvable group of symmetries of a system of ordinary differential equations allows to reduce by m the number of equations. We apply this principle by finding some affine derivations that induces expanded Lie point symmetries of considered system. By rewriting original problem in an invariant… (More)

Lie group theory states that knowledge of a m-parameters solvable group of symmetries of a system of ordinary differential equations allows to reduce by m the number of equation. We apply this principle by finding dilatations and translations that are Lie point symmetries of considered ordinary differential system. By rewriting original problem in an… (More)

This paper deals with the index reduction problem for the class of quasi-regular DAE systems. It is shown that any of these systems can be transformed to a generically equivalent first order DAE system consisting of a single purely algebraic (polynomial) equation plus an under-determined ODE (that is, a semi-explicit DAE system of differentiation index 1)… (More)

- Florent Rougier, Daniel Claude, Michel Maurin, Alexandre Sedoglavic, Michel Ducher, Stéphane Corvaisier +2 others
- 2002

1 The main constraints to the administration of aminoglycosides are risks of nephrotoxicity and ototoxicity which can lead to acute, renal and vestibular failure. In this article we will focus on nephrotoxicity. No reliable predictor of nephrotoxicity has been found to date. We have developed a deterministic model which describes the aminoglycoside… (More)