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This study was aimed at testing the hypothesis that serotoninergic receptors in the locus coeruleus (LC) play a role in bacterial lipopolysaccharide-induced fever. To this end, 5-HT1A (WAY-100635; 3 microg/100 nL) and 5-HT2A (ketanserin; 2 microg/100 nL) antagonists were microinjected into the LC and body temperature was monitored by biotelemetry. Intra-LC… (More)