Alexandre L. Rodrigues

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Gorlin-Goltz syndrome, or nevoid basal cell carcinoma syndrome (NBCCS), is a rare autosomal dominant disorder caused by mutations in the PTCH1 gene and shows a high level of penetrance and variable expressivity. The syndrome is characterized by developmental abnormalities or neoplasms and is diagnosed with 2 major criteria, or with 1 major and 2 minor(More)
This paper discusses extensions of the popular methods proposed by Geweke and Porter-Hudak [Geweke, J. and Porter-Hudak, S., 1983, The estimation and application of long memory times series models. Large-sample properties of parameter estimates for strongly dependent stationary Gaussian time series. Annals of Statistics, 14, 517–532.] for estimating the(More)
We study a stochastic lattice model describing the dynamics of coexistence of two interacting biological species. The model comprehends the local processes of birth, death, and diffusion of individuals of each species and is grounded on interaction of the predator-prey type. The species coexistence can be of two types: With self-sustained coupled time(More)
Maps of rates are often used for spatial dispersion analysis of certain event occurrence risk when data comes from counts by areas. However, the use of crude rates is associated to a high instability in expressing the risk of rare events in small population areas. As an alternative, will be introduced the empirical Bayesian rates; they make use either of(More)
This paper presents the study of the occurrence of 10 endocrine-disrupting compounds (EDCs) in 60 water samples using a method for simultaneous quantification and confirmation of the presence of these emerging compounds, using ultra-performance liquid chromatography with electrospray ionization and tandem mass spectrometry (UPLC-ESI-MS/MS). All samples were(More)
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