Alexandre Joannon

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Chemokines play a fundamental role in trafficking and activation of leukocytes in colonic inflammation. We investigated the ability of bindarit, an inhibitor of monocyte chemoattractant protein-1 (MCP-1/CCL2) synthesis, to inhibit chemokine production by human intestinal epithelial cells (HT-29) and its effect in trinitro-benzene sulfonic acid(More)
Agricultural changes such as intensification and specialization are thought to be the major source of the severe decline of farmland bird populations observed on large spatial scales and over long time spans in Europe. We studied farmers’ practices at a local level on 22 farms from the Beauce area, France, with regard to habitat preferences of grey(More)
Intensification and specialisation of agriculture in developed countries enabled productivity to be improved but had detrimental impacts on the environment and threatened the economic viability of a huge number of farms. The combination of livestock and crops, which was very common in the past, is assumed to be a viable alternative to specialised livestock(More)
Reducing pesticide use in agriculture is necessary to preserve natural resources. However, pest control without pesticides is a challenging issue. In particular, weed infestation may cause severe losses of crop yield. Weeds have been traditionally managed solely at the field level. However, larger scales must be considered because invasive and(More)
Applications regarding the crop allocation problem (CAP) are required tools for agricultural advisors to design more efficient farming systems. Despite this issue has been extensively treated by agronomists in the past, few methods tackle the crop allocation problem considering both the spatial and the temporal aspects of the CAP. In this paper, we(More)
This paper analyses the potential effect of local agro-environmental policies in promoting multifunctionality in a rural landscape, with a two-scale modelling framework: a regional scale for food demand and a local scale for the forces driving land use. The framework has been designed in four steps. First, the relative influence of the driving factors on(More)
Developing sustainable crop systems is a major challenge. Presently, management practices are simulated using either biophysical models or simple farmer decision models. As a result, there is a lack of generic models integrating both biophysical parameters and farmer decision parameters. Here, we developed an original graphical plug-in to sketch and(More)
This article proposes the use of a new model, DIAR (Diagnostic Agronomique du Ruissellement, or Agronomic Assessment of Runoff), for the prediction of the timing of the risk of runoff. DIAR is dedicated to loamy soils which are very sensitive to surface crusting, leading to runoff, soil erosion and muddy flows. The approach is proposed for the north-western(More)