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  • Alexandre Harari, Stéphanie Petitpierre, Florence Vallelian, Giuseppe Pantaleo
  • Biology, Medicine
  • Blood
  • 2004 (First Publication: 1 February 2004)
  • HIV-1- and cytomegalovirus (CMV)-specific CD4 T-cell-mediated antiviral immunity was evaluated by assessing the frequency of interleukin 2 (IL-2)- and interferon gamma (IFN-gamma)-secreting cellsExpand
  • Simone C. Zimmerli, Alexandre Harari, Cristina Cellerai, Florence Vallelian, Pierre-Alexandre Bart, Giuseppe Pantaleo
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2005 (First Publication: 17 May 2005)
  • Functional and phenotypic characterization of virus-specific CD8 T cells against cytomegalovirus, Epstein-Barr virus, influenza (flu), and HIV-1 were performed on the basis of the ability of CD8 TExpand
  • Alexandre Harari, Florence Vallelian, Pascal R. A. Meylan, Giuseppe Pantaleo
  • Medicine, Biology
  • The Journal of Immunology
  • 2005 (First Publication: 15 January 2005)
  • Memory CD4 T cell responses are functionally and phenotypically heterogeneous. In the present study, memory CD4 T cell responses were analyzed in different models of Ag-specific immune responsesExpand
  • Alexandre Harari, Valérie Dutoit, Cristina Cellerai, Pierre-Alexandre Bart, Renaud A Du Pasquier, Giuseppe Pantaleo
  • Biology, Medicine
  • Immunological reviews
  • 2006 (First Publication: 1 June 2006)
  • The most common human viruses have different abilities to establish persistent chronic infection. Virus-specific T-cell responses are critical in the control of virus replication and in theExpand
  • Selena Viganó, Daniel T Utzschneider, Matthieu Perreau, Giuseppe Pantaleo, Dietmar Zehn, Alexandre Harari
  • Medicine, Biology
  • Clinical & developmental immunology
  • 2012 (First Publication: 20 November 2012)
  • The functional avidity is determined by exposing T-cell populations in vitro to different amounts of cognate antigen. T-cells with high functional avidity respond to low antigen doses. This in vitroExpand
  • Alexandre Harari, Felicitas Bellutti Enders, Cristina Cellerai, Pierre-Alexandre Bart, Giuseppe Pantaleo
  • Medicine, Biology
  • Journal of Virology
  • 2009 (First Publication: 28 January 2009)
  • ABSTRACT Cytotoxic CD8 T cells exert their antiviral and antitumor activity primarily through the secretion of cytotoxic granules. Degranulation activity and cytotoxic granules (perforin plusExpand
  • Cristina Cellerai, Alexandre Harari, +11 authors Sabine Kinloch-de Loes
  • Biology, Medicine
  • PloS one
  • 2011 (First Publication: 5 April 2011)
  • Background Intervention with antiretroviral treatment (ART) and control of viral replication at the time of HIV-1 seroconversion may curtail cumulative immunological damage. We have thereforeExpand