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An Antigen Produced by Splicing of Noncontiguous Peptides in the Reverse Order
CD8-positive T lymphocytes recognize peptides that are usually derived from the degradation of cellular proteins and are presented by class I molecules of the major histocompatibility complex. HereExpand
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Splicing of Distant Peptide Fragments Occurs in the Proteasome by Transpeptidation and Produces the Spliced Antigenic Peptide Derived from Fibroblast Growth Factor-5
Peptide splicing is a newly described mode of production of antigenic peptides presented by MHC class I molecules, whereby two noncontiguous fragments of the parental protein are joined togetherExpand
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An antigenic peptide produced by reverse splicing and double asparagine deamidation
A variety of unconventional translational and posttranslational mechanisms contribute to the production of antigenic peptides, thereby increasing the diversity of the peptide repertoire presented byExpand
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Differences in the production of spliced antigenic peptides by the standard proteasome and the immunoproteasome
Peptide splicing allows the production of antigenic peptides composed of two fragments initially non‐contiguous in the parental protein. The proposed mechanism of splicing is a transpeptidationExpand
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Analysis of the Processing of Seven Human Tumor Antigens by Intermediate Proteasomes
We recently described two proteasome subtypes that are intermediate between the standard proteasome and the immunoproteasome. They contain only one (β5i) or two (β1i and β5i) of the three inducibleExpand
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Splicing of antigenic peptides by the proteasome
Antigens presented by MHC class I molecules to CD8+ T lymphocytes consist of peptides of 8-11 amino acids, corresponding to continuous fragments of intracellular proteins. However, some antigenicExpand
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This information is current as Proteasomes Tumor Antigens by Intermediate Analysis of the Processing of Seven Human Parmentier
We recently described two proteasome subtypes that are intermediate between the standard proteasome and the immunoproteasome. They contain only one (b5i) or two (b1i and b5i) of the three inducibleExpand