Alexandre C Capon

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BACKGROUND We previously reported that skin closure is improved by photoirradiation of the wound margins with an 815-nm diode laser system. OBJECTIVES To determine whether the beneficial effects of laser treatment involve the overexpression of the inducible 72-kDa heat shock protein, Hsp70. METHODS Expression of Hsp70 was investigated by(More)
BACKGROUND AND OBJECTIVE This study aimed to evaluate a 815-nm diode-laser system to assist wound closure to accelerate and improve healing process. STUDY DESIGN/MATERIALS AND METHODS A total of 25 male hairless rats (mutant OFA Sprague-Dawley rats, IFFA-CREDO, L'Arbresle, France) with four dorsal skin incisions were used for the study. For each wound,(More)
The use of lasers has been proposed for scar revision. A recent pilot clinical study demonstrated that lasers could also be used immediately after surgery to reduce the appearance of scars. The LASH (Laser-Assisted Skin Healing) technique induces a temperature elevation in the skin which modifies the wound-healing process. We report a prospective(More)
Lasers are now widely used for treating numerous cutaneous lesions, for scar revision (hypertrophic and keloid scars), for tissue welding, and for skin resurfacing and remodeling (wrinkle removal). In these procedures lasers are used to generate heat. The modulation of the effect (volatilization, coagulation, hyperthermia) of the laser is obtained by using(More)
BACKGROUND AND OBJECTIVE Selective dermal remodeling consists of inducing collagen tightening, neocollagen synthesis, or both, without damage to the overlying epidermis. This experimental study aimed to evaluate an Er:Glass laser emitting at 1.54 micrometer combined with contact cooling to target the upper dermis while protecting the epidermis. STUDY(More)
Relapsing polychondritis (RP) is a rare vasculitide characterized by recurrent inflammation of cartilagenous structures (auricular, nasal, laryngotracheal, articular) and specific sense organs (eyes and ear). Neurological complications are exceptional. We report the case of an elderly and previously well woman who presented with inflammatory syndrome and(More)
Laser-Assisted Skin Healing (LASH) is based on the therapeutic effects of controlled thermal post-conditioning. The authors have previously demonstrated on humans that an 810-nm diode-laser system could assist wound closure leading to an improvement of wound healing with a resulting indiscernible scar. A 47-year-old woman (skin type II), who developed(More)
Any cutaneous damage triggers a cascade of biological effects in the skin responsible for re-establishing skin integrity. Wound healing is a complex biological process inducing dermal remodelling leading at least to a visible scar, and sometimes to hypertrophic or keloid scars. Recent studies suggest that using a laser generates a precisely defined thermal(More)