Alexandre C. B. Delbem

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Network design involves several areas of engineering and science. Computer networks, electrical circuits, transportation problems, and phylogenetic trees are some examples. In general, these problems are NP-Hard. In order to deal with the complexity of these problems, some alternative strategies have been proposed. Approaches using evolutionary algorithms(More)
Several computational models have been developed in the context of the Protein Structure Prediction (PSP) problem. These methods involve a combinatorial problem and can be solved using optimizing algorithms in order to search for a global minimum energy. Genetic Algorithms (GAs) have produced relevant results in this area. Several energies in the protein(More)
This article focuses on the development of an approach for ab initio protein structure prediction (PSP) without using any earlier knowledge from similar protein structures, as fragment-based statistics or inference of secondary structures. Such an approach is called purely ab initio prediction. The article shows that well-designed multiobjective(More)
Case-Based Reasoning is a methodology for problem solving based on past experiences. This methodology tries to solve a new problem by retrieving and adapting previously known solutions of similar problems. However, retrieved solutions, in general, require adaptations in order to be applied to new contexts. One of the major challenges in Case-Based Reasoning(More)
Several variable selection algorithms in multivariate calibration can be accelerated using Graphics Processing Units (GPU). Among these algorithms, the Firefly Algorithm (FA) is a recent proposed metaheuristic that may be used for variable selection. This paper presents a GPU-based FA (FA-MLR) with multiobjective formulation for variable selection in(More)
The protein structure prediction problem continues to elude scientists. Despite the introduction of many methods, only modest gains were made over the last decade for certain classes of prediction targets. To address this challenge, a social-media based worldwide collaborative effort, named WeFold, was undertaken by 13 labs. During the collaboration, the(More)