Alexandra Joan Friel

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Objective: To investigate the independent influence of alterations in fat mass, body fat distribution and hormone release on pubertal increases in fasting serum insulin concentrations and on insulin resistance assessed by the homeostasis model (HOMA).Design and Subjects: Cross-sectional investigation of pre- (n=11, n=8), mid- (n=10, n=11), and late-pubertal(More)
___________________________ Date 3 ACKNOWLEDGEMENTS This thesis would not have been possible without the guidance and support of my brilliant professors, family, and friends. I wish to thank the following persons in particular: Dr. Dan Benardot to whom I am deeply indebted for his patience, counsel, and instruction throughout Vincent and Florence Friel my(More)
15017 Background: Ovarian cancer (OvCa) ranks fourth as the cause of death related to cancer in women in the U.S. The vast majority (>90%) of OvCa originates from the ovarian surface epithelium. There is sufficient evidence to suggest that hormones, especially estrogen, may be involved in the etiopathogenesis of epithelial OvCa. Recent studies indicate that(More)
The objective of this research was to assess current patterns of hospital antibiotic prescribing in Northern Ireland and to determine targets for improving the quality of antibiotic prescribing. A point prevalence survey was conducted in four acute teaching hospitals. The most commonly used antibiotics were combinations of penicillins including β-lactamase(More)
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