Alexandra E Kejner

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OBJECTIVES/HYPOTHESIS To evaluate bone invasion, survival, and expression of bone morphogenetic protein-6 (BMP-6) in oral cavity cancer in the context of known biomarkers indicative of poor prognosis. STUDY DESIGN Molecular expression study combined with retrospective chart review of corresponding patients at a tertiary care center. METHODS Between 2000(More)
BACKGROUND Advances in the care of patients with cystic fibrosis (CF) have improved pulmonary outcomes and survival. In addition, rapid developments regarding the underlying genetic and molecular basis of the disease have led to numerous novel targets for treatment. However, clinical and basic scientific research focusing on therapeutic strategies for(More)
OBJECTIVE An increasing number of head and neck surgeons have begun using transoral robotic-assisted surgery. Our objective was to examine the postoperative bleeding complications we have encountered to determine risk factors and to discuss the topic of hemorrhage control. STUDY DESIGN Case series with chart review. METHODS Medical records were reviewed(More)
The glossopharyngeal and vagus nerves mediate the complex interplay between the many functions of the upper aerodigestive tract. Defects may occur anywhere from the brainstem to the peripheral nerve and can result in significant impairment in speech, swallowing, and breathing. Multiple etiologies can produce symptoms. In this review, the authors broadly(More)
OBJECTIVE To describe a novel method for the removal of the salivary bypass tube (SBT) that precludes the need for extraction under general anesthesia. STUDY DESIGN Retrospective case series. METHODS/TECHNIQUE Patients who had undergone laryngectomy/laryngopharyngectomy with subsequent development of pharyngocutaneous fistula and intraoperative(More)
OBJECTIVES/HYPOTHESIS Evaluate outcomes of the standard static sling and orthodromic temporalis tendon transfer reanimation for facial nerve paralysis. STUDY DESIGN Retrospective case series at a tertiary care hospital of head and neck cancer patients with facial nerve palsy secondary to malignancy or resection. METHODS From 2004 to 2014, patients(More)
OBJECTIVE To evaluate perioperative mortality after tracheostomy in intensive care unit (ICU) patients undergoing routine tracheostomy over a 10-month period. STUDY DESIGN Case series with planned data collection. SETTING Tertiary care hospital. SUBJECTS Mechanically ventilated patients. METHODS Prospective analysis of ICU patients undergoing(More)
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