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BRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradation
The BRCA1 tumor suppressor protein heterodimerizes with its partner protein, BARD1, via the RING domain present in both proteins. The heterodimer contains an E3 ubiquitin ligase activity andExpand
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Alteration of mammary gland development and gene expression by in utero exposure to arsenic.
Early life exposure to estrogens and estrogen like contaminants in the environment is thought to contribute to the early onset of puberty and consequently increases the risk of developing breastExpand
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Alteration of Mammary Gland Development and Gene Expression by In Utero Exposure to Cadmium
Environmental exposure to estrogens and estrogen like contaminants during early development is thought to contribute to the risk of developing breast cancer primarily due to an early onset ofExpand
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Rituximab-mediated ADCC is augmented by concomitant interference with inhibitory self-recognition by human NK cells
Proc Amer Assoc Cancer Res, Volume 47, 2006 635 The anti-CD20 monoclonal antibody, rituximab, is widely used in the treatment of non-Hodgkin lymphomas. However, clinical responses to rituximab areExpand