Alexandr Kirichenko

Learn More
Ozone is a photochemically generated pollutant that can cause acute pulmonary inflammation and induce cellular injury and may contribute to the development or exacerbation of chronic lung diseases. Despite extensive investigation, the mechanisms of ozone and oxidant-induced cellular injury are still uncertain. Ozone has been reported to cause the formation(More)
Oxidative stress is known to cause apoptosis in many cell types, yet the mechanism of oxidative stress-induced apoptosis is not clear. Oxidative stress has been described to cause peroxidation of polyunsaturated fatty acids. 4-Hydroxynonenal (HNE) is a diffusible product of lipid peroxidation and has been shown to be toxic to cells. In this study, the(More)
Acknowledgments First and foremost I am happy to have a chance to express my deepest gratitude to both of my advisors, Professor Sanjay K. Banerjee and Professor Geyong S. Hwang. I have been exceptionally fortunate to be working under their joint supervision. I greatly thank Professor Banerjee for giving me inspiration , intellectual freedom and(More)
Using s u b s t i t u t e d b e n z o y l c h l o r i d e s and c h l e r o a c e t y l c h l o r i d e , a number of 6 a r y l ( I a f ) and 6 c h l o r o m e t h y l ( I g ) b e n z i m i d a z o [ 1 , 2 c ] q u i n a z o l i n e s have been o b t a i n e d . Compounds ( I f ) and ( I g ) , which c o n t a i n a r e a c t i v e h a l o g e n a tom, a r e(More)
  • 1