Alexander Yu Meigal

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The purpose of the study was to evaluate linear and nonlinear tremor characteristics of the hand in patients with Parkinson's disease (PD) and to compare the results with those of healthy old and young control subjects. Furthermore, the aim was to study correlation between tremor characteristics and clinical signs. A variety of nonlinear (sample entropy,(More)
The influence of cold (+5 degrees C), room temperature (+22 degrees C) and hot (+75 degrees C) air exposures on postactivation effects (PAE) in brachial biceps (BBs) and triceps (TBs) muscles were investigated bilaterally in six male subjects. PAE were evoked by 1 min volitional isometric contraction (VIC) at submaximal level in BBs by holding an inertial(More)
BACKGROUND Exposure to cold impairs manual performance through effects on muscle tissue and control mechanisms. The purpose of this study was to assess the influence of increased muscle tone and shivering on ability to maintain required force during isometric flexion over a wide range of effort levels. METHODS Lightly clad male subjects (n = 6) were(More)
The aim of the investigation was to determine the effects of cold shivering on the accuracy of force output in distal, middle and proximal muscles of the upper limb. Test of hand grip strength, elbow flexion and shoulder flexion (each done at 10% maximal voluntary contraction for 15 s) were done under three conditions: (1) thermoneutral air (27 degrees C),(More)
Here we describe GATO (gravity, age, thermoregulation, and oxygenation) hypothesis (or a "Baby Astronaut" hypothesis) which we suggest to explain synergistic effect of these factors on the motor system. Taken separately, microgravity (in spaceflight, G~0), the early age, heat and hypoxia exert identical effect on the motor system. We posit that synergy of(More)
Electromyograms (EMGs) were recorded from both deltoid muscles (DMs) when subjects were sitting, standing, and bending the head laterally at different cold sensations to clarify the role of head and body positions in the thermoregulatory tonus. At room temperature (22 degrees C), neither EMG related to thermoregulatory muscle tonus (TMT) nor were changes in(More)
The article presents data on new approaches to the application of the surface electromyogram based on the nonlinear dynamics of complex systems. Special focus is placed on applicability of nonlinear parameters for early and differential diagnostics of Parkinson's disease, various kinds of tremor, schizophrenia, as well as for the estimation of normal(More)
The presented investigation was designed to elucidate whether age impacts the basic neurophysiological characteristics of motor unit (MU) thermoregulatory activity in human subjects. Human newborns and infants (aged from 7 days to 3 years, n = 81) were exposed to ambient temperatures of 26-27 degrees C for 5-7 minutes. The adults and elderly (18-76 years(More)
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