Alexander V Zhukotskii

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A study was designed to document and quantify the changes in lens clarity over 6 and 24 months in 2 groups of 49 volunteers (76 eyes) with an average age of 65.3 +/- 7.0 enrolled at the time of diagnosis of senile cataracts of minimal to advanced opacification. The patients received N-acetylcarnosine, 1% sol (NAC) (26 patients, 41 eyes = Group II), placebo(More)
Glucocorticoid-induced cataracts in chick embryos were monitored by an image analysis system. Opacities in the lens visually showed a complex pattern with significant changes in the cortical and nuclear regions. An electronic image analyser produced an image in which contrast represented different zones of lens opacification in the frontal plane and(More)
The changes of hepatic mitochondrial cells were studied in white male rats during internal application of boron-containing waters, having 250 mg/l concentration of boron, but different ionic-salt basis. Mitochondrial hepatocytes and hepatic boron content relationships were established. It was shown that during boron accumulation in liver (15 applications)(More)
PURPOSE To evaluate the effects of 1% N-acetylcarnosine (NAC) solution on lens clarity over 6 and 24 months in patients with cataracts. TRIAL DESIGN Randomised, placebo-controlled study. PARTICIPANTS 49 subjects (76 affected eyes) with an average age of 65.3 +/- 7.0 years with a diagnosis of senile cataract with minimum to advanced opacification in(More)
BACKGROUND A new glare disability test and a diagnostic instrument, the Halometer, were proposed for measuring intraocular light scattering in the presence of human cataracts. The objectives of this work were to introduce new methods of computer-generated analysis of lens images and a glare disability test to validate the use of two new tests to measure the(More)
Mycoplasma hominis was incubated with HeLa cells up to 72 h. Infection of HeLa cells was estimated by in situ polymerase chain reaction with a subsequent use of computer digital image analysis for result processing. The localization of mycoplasma in the cell nucleus was demonstrated after a 48 h incubation. The quantity of infected HeLa cells was increased(More)
In patients with atherosclerotic encephalopathy (AE) the major indices of blood rheology, hemostasis and its cells' functional state were under investigation. Different patterns of blood rheology changes were detected with increased counts of pathological red blood cells and hypercoagulability. These disorders correlated with the rate of major neurological(More)
Several pathological states are linked with disturbances of the rheologic properties of the blood, which are largely dependent on erythrocyte deformability [6]. Consequently, assessment of erythrocyte deformability by the use of the filterability test on blood samples is becoming increasingly important. As a rule what is measured is the number of(More)
It has been shown in experimental chronic intoxication that there is a close correlation between the dose of ethanol, microscopic appearance of the liver, the content of DNA, RNA, protein, glycogen in hepatocytes and structural parameters of nuclear chromatin of these cells. It is concluded that automatic cytophotometric analysis of the structure of(More)
A further improvement in the quality of morphologic diagnosis of kidney diseases can be achieved through objectivization of morphologic investigations [1] by the wider use of quantitative methods [6]. Quantification of a pathological process also enables correlation analysis to be undertaken, with the detection of parallel trends in morphology and function(More)