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Cellular delivery of small interfering RNA by a non-covalently attached cell-penetrating peptide: quantitative analysis of uptake and biological effect
- Sandra Veldhoen, Sandra D. Laufer, Alexander Trampe, T. Restle
- Biology, Medicine
- Nucleic acids research
- 28 November 2006
Cell-penetrating peptides (CPPs) have evolved as promising new tools to deliver nucleic acids into cells. So far, the majority of these delivery systems require a covalent linkage between carrier and… Expand
Noncovalent peptide-mediated delivery of chemically modified steric block oligonucleotides promotes splice correction: quantitative analysis of uptake and biological effect.
- Sandra D. Laufer, A. Recke, Sandra Veldhoen, Alexander Trampe, T. Restle
- Medicine, Biology
- 27 February 2009
Despite numerous encouraging reports in the literature, the efficiency of cell penetrating peptides (CPPs) in promoting cellular delivery of bioactive cargos is still limited. To extend our current… Expand