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The ability to sequence cost-effectively all of the coding regions of a given individual genome is rapidly approaching, with the potential for whole-genome resequencing not far behind. Initiatives are currently underway to phenotype hundreds of thousands of individuals for major human traits. Here, we determine the power for de novo discovery of genes(More)
MOTIVATION Although many methods and statistical approaches have been developed for protein identification by mass spectrometry, the problem of accurate assessment of statistical significance of protein identifications remains an open question. The main issues are as follows: (i) statistical significance of inferring peptide from experimental mass spectra(More)
For a binary sequence <i>Sn</i> = {<i>si</i>: <i>i</i>=1,2,...,<i>n</i>} ¿ {±1}<i>n</i>, <i>n</i> &gt; 1, the peak sidelobe level (PSL) is defined as M(S<sub>n</sub>)=max<sub>k=1,2,...,n-1</sub>|¿<sub>i=1</sub> <sup>n-k</sup>S<sub>i</sub>S<sub>i</sub>+k|. It is shown that the distribution of <i>M</i>(<i>Sn</i>) is strongly concentrated, and asymptotically(More)
Citation Graham, Noah et al. " Casimir force at a knife's edge. Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters.
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