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MOTIVATION
Although many methods and statistical approaches have been developed for protein identification by mass spectrometry, the problem of accurate assessment of statistical significance of protein identifications remains an open question. The main issues are as follows: (i) statistical significance of inferring peptide from experimental mass spectra… (More)

For a binary sequence Sn = {s It is shown that the distribution of M (S n) is strongly concentrated, and asymp-totically almost surely, γ(Sn) = M (Sn) √ n ln n ∈ [1 − o(1), √ 2]. Explicit bounds for the number of sequences outside this range are provided. This improves on the best earlier known result due to Moon and Moser [19] claiming that the typical γ(S… (More)

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