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BACKGROUND Patients with cerebral cavernomas have an estimated risk of the development of epilepsy of 1.5% to 2.4% per patient-year. OBJECTIVE To clarify the predictive value of different risk factors for epilepsy in patients with supratentorial cavernomas. METHODS We retrospectively analyzed data of 109 patients with supratentorial cavernomas. The(More)
In children with cleft lip and palate speech disorders appear often. One major disorder amongst them is hypernasality. This is the first study which shows that it is possible to automatically detect hyper-nasality in connected speech without any invasive means. Therefore, we investigated MFCCs and pronunciation features. The pronunciation features are(More)
The successful transfer of clinical practice guidelines (CPGs) into patient care depends on the appropriateness of the implementation method. This study strived for a better understanding of which intervention strategy is effective in implementing the CPG on Parkinson's disease (CPG-PD). In a cluster randomized controlled trial, we compared the impact of(More)
Propensity scoring (PS) is an established tool to account for measured confounding in non-randomized studies. These methods are sensitive to missing values, which are a common problem in observational data. The combination of multiple imputation of missing values and different propensity scoring techniques is addressed in this work. For a sample of lymph(More)
BACKGROUND Incomplete surgical staging is a negative prognostic factor for patients with borderline ovarian tumours (BOT). However, little is known about the prognostic impact of each individual staging procedure. METHODS Clinical parameters of 950 patients with BOT (confirmed by central reference pathology) treated between 1998 and 2008 at 24 German AGO(More)
BACKGROUND Surgical site infections are the third most frequent type of nosocomial infections. Evidence-based recommendations have been given regarding preoperative hospitalization, hygiene and air-conditioning, patient conditions, and wound dressing. However, no general recommendations concerning wound closure exist. Systematic reviews and meta-analyses(More)
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