Structure and Absolute Configuration of Pseudohygrophorones A(12) and B(12), Alkyl Cyclohexenone Derivatives from Hygrophorus abieticola (Basidiomycetes).
- Alexander Otto, A. Porzel, Jürgen Schmidt, W. Brandt, L. Wessjohann, N. Arnold
- ChemistryJournal of Natural Products
- 22 January 2016
The isolated compounds 1-3 exhibited pronounced activity against phytopathogenic organisms and a clear distinction between the pseudohygrophorones (1 and 2) and hygrophorone B(12) (3).
Isolation and Asymmetric Total Synthesis of Fungal Secondary Metabolite Hygrophorone B12
Hygrophorone B12, a new antifungal constituent from the fruiting bodies of Hygrophorus abieticola, has been isolated and subsquently synthesized in enantiomerically pure form, allowing the unambiguous control of all three stereogenic centres.
Chilenopeptins A and B, Peptaibols from the Chilean Sepedonium aff. chalcipori KSH 883.
A taxonomic study of the strain using molecular data of the ITS, EF1-α, and RPB2 barcoding genes confirmed the position of the isolated strain within the S. chalcipori clade, but also suggested the separation of this clade into three different species.
Isolation and Asymmetric Total Synthesis of Fungal Secondary Metabolite Hygrophorone B12.
Isolation and Total Synthesis of Albupeptins A–D: 11-Residue Peptaibols from the Fungus Gliocladium album
Four new 11-mer peptaibols, named albupeptins A–D (1–4), were isolated from cultures of the fungus Gliocladium album. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy, as…
Structural and stereochemical elucidation of new hygrophorones from Hygrophorus abieticola (Basidiomycetes)
Discovery of pyridine-2-ones as novel class of multidrug resistance (MDR) modulators: first structure-activity relationships.
A study on the biosynthesis of hygrophorone B(12) in the mushroom Hygrophorus abieticola reveals an unexpected labelling pattern in the cyclopentenone moiety.
Penarines A-F, (nor-)sesquiterpene carboxylic acids from Hygrophorus penarius (Basidiomycetes).
On mirror maps for manifolds of exceptional holonomy
We study mirror symmetry of type II strings on manifolds with the exceptional holonomy groups G2 and Spin(7). Our central result is a construction of mirrors of Spin(7) manifolds realized as…