Learn More
Resting cortical activity is characterized by a distinct spectral peak in the alpha frequency range. Slowing of this oscillatory peak toward the upper theta-band has been associated with a variety of neurological and neuropsychiatric conditions and has been attributed to altered thalamocortical dynamics. Children born very preterm exhibit altered(More)
Linearly constrained minimum variance beamformers are highly effective for analysis of weakly correlated brain activity, but their performance degrades when correlations become significant. Multiple constrained minimum variance (MCMV) beamformers are insensitive to source correlations but require a priori information about the source locations. Besides the(More)
Children born very prematurely (< or =32 weeks) often exhibit visual-perceptual difficulties at school-age, even in the absence of major neurological impairment. The alterations in functional brain activity that give rise to such problems, as well as the relationship between adverse neonatal experience and neurodevelopment, remain poorly understood.(More)
Children born very preterm (≤32 weeks gestational age) without major intellectual or neurological impairments often express selective deficits in visual-perceptual abilities. The alterations in neurophysiological development underlying these problems, however, remain poorly understood. Recent research has indicated that spontaneous alpha oscillations are(More)
Children born very preterm, even with broadly normal IQ, commonly show selective difficulties in visuospatial processing and executive functioning. Very little, however, is known what alterations in cortical processing underlie these deficits. We recorded MEG while eight children born very preterm (≤32 weeks gestational age) and eight full-term controls(More)
Children born very preterm, even when intelligence is broadly normal, often experience selective difficulties in executive function and visual-spatial processing. Development of structural cortical connectivity is known to be altered in this group, and functional magnetic resonance imaging (fMRI) evidence indicates that very preterm children recruit(More)
The human mirror neuron system is thought to be the underlying basis of perception-action coupling involved in imitation and action understanding. In order to examine this issue we examined the recruitment of the mirror neuron system, as reflected in mu rhythm suppression in a population of adults with Down syndrome (DS) with known strengths in imitation(More)
Local alpha-band synchronization has been associated with both cortical idling and active inhibition. Recent evidence, however, suggests that long-range alpha synchronization increases functional coupling between cortical regions. We demonstrate increased long-range alpha and beta band phase synchronization during short-term memory retention in children(More)
Minimum variance beamformers are popular tools used in EEG and MEG for analysis of brain activity. In recent years new multi-source beamformer methods were developed, including the Dual-Core Beamformer (DCBF) and its enhanced version (eDCBF). Both techniques should allow modeling of correlated brain activity under a wide range of conditions. However, the(More)
How humans understand the actions and intentions of others remains poorly understood. Here we report the results of a magnetoencephalography (MEG) experiment to determine the temporal dynamics and spatial distribution of brain regions activated during execution and observation of a reach to grasp motion using real world stimuli. We show that although both(More)