Alexander Lange

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The signaling molecule nitric oxide (NO), first described as endothelium-derived relaxing factor (EDRF), acts as physiological activator of NO-sensitive guanylyl cyclase (NO-GC) in the cardiovascular, gastrointestinal, and nervous systems. Besides NO-GC, other NO targets have been proposed; however, their particular contribution still remains unclear. Here,(More)
AIM High-grade Ewing sarcomas and Primitive neuroectodermal tumours (PNET) make up the tumours of the Ewing family. Our purpose was to evaluate the value of [18F]fluorodeoxyglucose positron emission tomography (FDG PET) in patients with Ewing tumours. PATIENTS AND METHODS Twenty-four patients who had PET because of a suspected Ewing tumour during a 5-year(More)
The NO/cGMP signaling pathway plays a major role in the cardiovascular system, in which it is involved in the regulation of smooth muscle tone and inhibition of platelet aggregation. Under pathophysiological conditions such as endothelial dysfunction, coronary artery disease, and airway hyperreactivity, smooth muscle containing arteries and bronchi are of(More)
The amounts of Sr90 taken up from Vina soil varied among several different crop plants by a factor as high as 10 on the basis of dry weight. The relative decreasing order of Sr90 uptake by mature plant tops was turnip = millet > Swiss chard > Ladino clover > broccoli > soybeans > barley > oats > wheat > spinach. For each of the cereal crops, the(More)
The estrous cycle of mono-ovulatory species such as cows or humans, is known to show two or more waves of follicular growth and decline between two successive ovulations. Within each wave, there is one dominant follicle escorted by subordinate follicles of varying number. Under the surge of the luteinizing hormone a growing dominant follicle ovulates.(More)
Organic solar cells are a favorable alternative to their inorganic counterparts because the functional layers of these devices can be processed with printing or coating on a large scale. In this study, a novel polymer was synthesized, blended with fullerene and deposited with inkjet printing for solar cell applications. Devices with printed layers were(More)
BACKGROUND Immunocytochemistry is the standard method for detection of disseminated breast-cancer cells. Tumor-cell enrichment by cell culture has been used by several investigators, however assays published have not been well-standardized. METHODS Breast-cancer cells from two lines were diluted in hemopoietic cells of varying origins and cultured in(More)
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