Alexander Lamb

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We have measured the distribution of intracellular calcium concentration in isolated single muscle fibres from Xenopus laevis using the fluorescent calcium indicator fura-2 with digital imaging fluorescence microscopy. Under control conditions, resting and tetanic calcium were uniform throughout a fibre. When fatigue was produced using a prolonged,(More)
Schubert (1984) and Kater et al. (1988) have suggested that motility and growth at the neuronal growth cone is activated by an increase of cytosolic free calcium concentration ([Ca2+]i) above the levels found in quiescent growth cones. In order to test this model, we have used a digital imaging fluorescence microscope together with injection of the(More)
The authors present a two-year experience with an approach aimed at federating applications into a component-based hospital-wide clinical information system. Recognizing the need for better integration, clearer separation of knowledge from applications, as well as the necessity to respect and integrate the diversity of roles in a healthcare network, a(More)
This paper presents how acquisition, storage and communication of clinical documents is implemented at the University Hospitals of Geneva. Careful attention has been given to user-interfaces, in order to support complex layouts, spell checking, and templates management with automatic prefilling. A dual architecture has been developed for storage using an(More)
Digital physics seeks to help answer problematic open questions in quantum gravity by bringing to bear techniques from computer science. One approach to this endeavor is the creation of a toolbox of algorithms that can reliably simulate basic quantum phenomena. To facilitate this goal, we explore the extent to which set-based, pseudo-particle algorithms and(More)
The primary goal of digital physics research is to provide a description of the physical universe in terms of simple programs. One approach to attaining this goal is creating a toolbox of algorithms that reproduce the behavior of basic quantum phenomena. As a step in this direction, a simple pseudo-particle algorithm has been developed that exhibits(More)
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