Alexander Klassmann

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Despite its scientific, political, and practical value, comprehensive information about human languages, in all their variety and complexity, is not readily obtainable and searchable. One reason is that many language data are collected as audio and video recordings which imposes a challenge to document indexing and retrieval. Annotation of multimedia data(More)
Tests of the neutral evolution hypothesis are usually built on the standard null model which assumes that mutations are neutral and the population size remains constant over time. However, it is unclear how such tests are affected if the last assumption is dropped. Here, we extend the unifying framework for tests based on the site frequency spectrum,(More)
We present an exact, closed expression for the expected neutral Site Frequency Spectrum for two neutral sites, 2-SFS, without recom-bination. This spectrum is the immediate extension of the well known single site θ/f neutral SFS. Similar formulae are also provided for the case of the expected SFS of sites that are linked to a focal neutral mutation of known(More)
Identifying genomic regions with unusually high local haplotype homozygosity represents a powerful strategy to characterize candidate genes responding to natural or artificial positive selection. To that end, statistics measuring the extent of haplotype homozygosity within (e.g., EHH, iHS) and between (Rsb or XP-EHH) populations have been proposed in the(More)
The " download first, then process paradigm " is still the predominant working method amongst the research community. The web-based paradigm, however, offers many advantages from a tool development and data management perspective as they allow a quick adaptation to changing research environments. Moreover, new ways of combining tools and data are(More)
A tool set to create complex multimedia/multimodal annotations and to exploit them is described. Due to its possibility to flexibly define tiers and associate languages/writing systems with it and to even mix characters from different writing systems it is a tool which is especially suitable for work in multilingual environments. Also the search interface(More)
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