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Attention deficit hyperactivity disorder (ADHD) is the most common neurobehavioral disorder, affecting 3% to 5% of school-aged children. Of the 3 subtypes--predominantly inattentive, predominantly hyperactive/impulsive, and a combined subtype--the latter is the most commonly represented group, accounting for 50% to 70% of all ADHD individuals. Stimulant(More)
The effects of Bmp-4 on interdigital cell death were investigated in the mouse. Affi-Gel beads, loaded with recombinant Bmp-4 protein, were transplanted into the interdigital tissues of day 12.5 hindlimb, ex utero. It was established that Bmp-4 could induce precocious interdigital cell death. Using in situ hybridization, the expression patterns of bmp-4 and(More)
Atopic eczema or dermatitis (AD) is a chronically relapsing dermatitis associated with pruritus, sleep disturbance, psychosocial symptoms, and impaired quality of life. It affects 10-20 % of school-aged children, and there is evidence to suggest that this prevalence is increasing. Filaggrin (filament-aggregating protein) has an important function in(More)
Henoch-Schönlein purpura is a fairly common pediatric disorder. The role of immunosuppression in the treatment of HSP continues to be controversial and awaits a multicenter controlled trial. The prognosis for the majority of patients is very good. Less than 2% of patients develop a serious complication associated with long-term morbidity. The most common(More)
A delay in speech development may be a symptom of many disorders, including mental retardation, hearing loss, an expressive language disorder, psychosocial deprivation, autism, elective mutism, receptive aphasia and cerebral palsy. Speech delay may be secondary to maturation delay or bilingualism. Being familiar with the factors to look for when taking the(More)
Asthma is a prevalent childhood atopic disease associated with significant impairment of quality of life. Management relies on avoidance of triggers such as food and aeroallergens, the use of inhaled bronchodilators/corticosteroids and anti-allergic or immune-modulating therapies. Inhaled corticosteroids (ICSs) and bronchodilators have been the mainstay of(More)
  • A K Leung
  • 1986
I conducted a retrospective study based on record reviews of 50,892 infants born at the Foothills Provincial Hospital, Calgary, Alberta, Canada, from 1967 to 1984 to determine the incidence and possible causes of natal teeth. Fifteen infants were affected, for an incidence rate of one in 3,392 births. The affected teeth were the lower central incisors. The(More)
MLNS is the most common cause of nephrotic syndrome in childhood and has a very good prognosis. Other histologic types have a varying prognosis. Corticosteroid treatment induces a remission in the majority of patients with nephrotic syndrome. Every effort should be made to reduce the total dose of corticosteroid so as to minimize the potential for(More)