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  • William M. Foster, Alexander Helm, +4 authors William R. Skach
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2000 (First Publication: 3 November 2000)
  • Homologous aquaporin water channels utilize different folding pathways to acquire their transmembrane (TM) topology in the endoplasmic reticulum (ER). AQP4 acquires each of its six TM segments viaContinue Reading
  • Ya Qing Lu, Xiong Xiong, Alexander Helm, K Kimani, A. G. Bragin, William R. Skach
  • Biology, Medicine
  • The Journal of biological chemistry
  • 1998 (First Publication: 2 January 1998)
  • Transmembrane topology of most eukaryotic polytopic proteins is established cotranslationally at the endoplasmic reticulum membrane through the action of alternating signal and stop transferContinue Reading
  • K Moss, Alexander Helm, Yong Xiang Lu, Alvina Bragin, William R. Skach
  • Medicine, Biology
  • Molecular biology of the cell
  • 1998 (First Publication: 1 September 1998)
  • Topogenic determinants that direct protein topology at the endoplasmic reticulum membrane usually function with high fidelity to establish a uniform topological orientation for any given polypeptide.Continue Reading
  • Franziska Hessel, Mechthild Krause, +4 authors Michael Baumann
  • Biology, Medicine
  • International journal of radiation biology
  • 2004 (First Publication: 1 October 2004)
  • PURPOSE To investigate the magnitude and kinetics of repopulation in a moderately well differentiated UT-SCC-14 human squamous cell carcinoma [hSCC] in nude mice. This question is of interest becauseContinue Reading
  • Alexander Helm, Onetsine Arrizabalaga, Diana Pignalosa, Insa S. Schroeder, Marco Durante, Sylvia Ritter
  • Medicine, Biology
  • Stem cells and development
  • 2016 (First Publication: 15 January 2016)
  • Little is known about the effects of ionizing radiation on the earliest stages of embryonic development although it is well recognized that ionizing radiation is a natural part of our environment andContinue Reading