Alexander Gruenberger

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In this protocol the fabrication, experimental setup and basic operation of the recently introduced microfluidic picoliter bioreactor (PLBR) is described in detail. The PLBR can be utilized for the analysis of single bacteria and microcolonies to investigate biotechnological and microbiological related questions concerning, e.g. cell growth, morphology,(More)
A disposable microfluidic chip system for single cell analysis is presented. The device enables hydrodynamic trapping of single bacteria cells of various industrial prokaryotic strains, e.g., E. coli and C. glutamicum, in partly sub-µm fluidic structures. Single cell traps are arranged in arrays aiming for quasi high-throughput cell observation with respect(More)
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