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What is the meaning associated with a single action potential in a neural spike train? The answer depends on the way the question is formulated. One general approach toward formulating this question involves estimating the average stimulus waveform preceding spikes in a spike train. Many different algorithms have been used to obtain such estimates, ranging(More)
A powerful approach to studying how information is transmitted in basic neural systems is based on finding stimulus-response classes that optimize the mutual information shared between the classes [2,6]. The problem can be formally described in terms of finding a optimal quantization´µ of a large discrete joint´µ distribution and various algorithms have(More)
We propose a model for the lateral connectivity of orientation-selective cells in the visual cortex. We study the properties of the input signal to the visual cortex and find new statistical structures that have not been processed in the retino-geniculate pathway. Using the idea that the system performs redundancy reduction of the incoming signals, we(More)
A simple mathematical model for the large{scale circuitry of primary visual cortex is introduced. It is shown that a basic cor-tical architecture of recurrent local excitation and lateral inhibition can account quantitatively for such properties as orientation tuning. The model can also account for such local effects as cross{orientation suppression. It is(More)
Some myopathies are accompanied by abnormal calcium homeostasis. Electromyography (EMG) in such patients shows signs of normal or myopathic EMG when detected by a single-fiber electrode and abnormally increased values in macro EMG. As calcium accumulation might be accompanied by changes in intracellular action potential (IAP) and muscle-fiber propagation(More)
We discuss an analytical approach through which the neural symbols and corresponding stimulus space of a neuron or neural ensemble can be discovered simultaneously and quantitatively, making few assumptions about the nature of the code or relevant features. The basis for this approach is to conceptualize a neural coding scheme as a collection of(More)
Generally the anatomy of muscles is rather complex, and the fibres have various inclination angles within the muscles. We suggest a fast and reliable way to calculate extracellular potentials produced at a point or rectangular plate electrode by a muscle fibre of finite length with an arbitrary inclination. A muscle fibre was considered to be a linear(More)