Alexander Chan

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Extracellular surface proteins are used to identify fully-functional human mesenchymal stem cells (hMSCs) in a mixed population. Here, a multiparameter flow cytometry assay was developed to examine the expression of several bone marrow-derived hMSC markers simultaneously at the single cell level. The multiparameter approach demonstrates a depth of analysis(More)
Introduction As databases of protein sequences and properties increase in size, it becomes more and more reliable to depend on previously classified proteins to determine the structure and function of a novel protein. One method of determining homology between two proteins is through a pair-wise sequence alignment of their primary structures. It has been(More)
Recent experimental and computational advances in the protein folding arena have shown that the readout of the one-dimensional sequence information into three-dimensional structure begins within the first few microseconds of folding. The initiation of refolding reactions has been achieved by several means, including temperature jumps, flash photolysis,(More)
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